Palazzo Santa Maria is more than a hotel—it’s a living expression of Syros’ Golden Era, lovingly restored with the spirit of true hospitality. Built in 1874 and perched on the west hillside of Hermoupolis, our mansion blends neoclassical grandeur with modern comfort, just a short walk from the city’s cultural heart.
Step inside and you’ll find hand-restored frescoes, antique furnishings, and a carefully curated art collection—including works by Yannis Moralis and Giota Sotiriou—each piece telling its own story. Every room has been designed to honour the building’s 150-year legacy, with original details preserved and elevated through thoughtful, meticulous renovation.
This is a deeply personal project—born from a lifelong passion for hospitality and shaped by over 40 years of international experience. Whether you’re here to explore Hermoupolis or simply soak up the quiet elegance of your surroundings, we promise an experience rooted in history, beauty, and genuine care. Palazzo Santa Maria is a place to pause, feel, and remember.
With just six carefully curated rooms, Palazzo Santa Maria promises a boutique stay that feels both personal and refined. Choose from our spacious Junior Suites, the elegant Santa Maria Premier, or the character-rich Palazzo Classic—each featuring luxurious Beautyrest by Simmons beds and thoughtful design details. Ranging from 18 to 32m², each room has its own character, combining comfort with a sense of place—set within the historic walls of our neoclassical home.
Breakfast at Palazzo Santa Maria is a relaxed, flavourful start to the day, served in our intimate restaurant and lounge. We offer a carefully curated selection of local delicacies—freshly prepared and rooted in the culinary traditions of Syros. Whether you linger over coffee or start early for a day of exploring, breakfast here is always something to look forward to.
At Palazzo Santa Maria, sustainability is part of our everyday rhythm. From energy-efficient systems and eco-certified cleaning products to thoughtful linen policies and recycling, we’re committed to reducing our footprint without compromising on comfort. We work closely with suppliers who prioritise sustainable practices and minimal packaging, ensuring our efforts support both the environment and our wider community. It’s hospitality with care—for our guests and our island.
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